Application
CRADD Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the CRADD antibody detected the CRADD protein (arrow).| Product Name | CRADD Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CRADD; RAIDD; Death domain-containing protein CRADD; Caspase and RIP adapter with death domain; RIP-associated protein with a death domain |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | RAIDD |
|---|---|
| Alternative Names | CRADD RAIDD Death domain-containing protein CRADD Caspase and RIP adapter with death domain RIP-associated protein with a death domain |
| Molecular Weight(MW) | 22745 Da |
| Function | Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex |
| Tissue Specificity | Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney |
| Cellular Localization | Cytoplasm (By similarity). Nucleus (By similarity) |
| Entrez Gene | 8738 |
|---|---|
| Nucleotide Accession | NP_003796.1 |
Application
CRADD Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the CRADD antibody detected the CRADD protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
