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S100A1 Antibody

Catalog Number:OM220400
OM220400
Discount Price
OM220400-100ul
1~2 Week
100ul
OM220400-50ul
50ul
1~2 Week
Product Profile
Product Name S100A1 Antibody
Antibody Type Primary Antibodies
Antigen Alias S100; S100A; S100-alpha; S100A1
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 2C8B8, 2C8E8,3C8D8
Host Species Mouse
Tested Applications WBIHC
WB:1:500 - 2000. IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms S100A
Alternative Names S100
S100A
S100-alpha
S100A1
Molecular Weight(MW) 10546 Da
Function Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites
Tissue Specificity Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain
Cellular Localization Cytoplasm.
Database Links
Entrez Gene 6271
Nucleotide Accession NP_006262.1
Application

Application

Figure 1: Western blot analysis using anti-S100A monoclonal antiobdy against truncated S100A recombinant protein.

Application

Figure 2: Immunohistochemical analysis of paraffin-embedded human brain tissue(A), lymphoid follicles tissue(B) and interbrain tissue(C), showing cytoplasmic localization using anti-S100A antibody with DAB staining.
Application Notes WB:1:500 - 2000. IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified recombinant fragment of S100A1 expressed in E. Coli.
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