SEMA6A Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SEMA6A antibody detected the SEMA6A protein (arrow).
SEMA6A KIAA1368 SEMAQ Semaphorin-6A Semaphorin VIA Semaphorin-6A-1
Molecular Weight(MW)
114395 Da
Function
Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation (By similarity)
Tissue Specificity
This SEMA6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 696-728 amino acids from the Central region of human SEMA6A.
Cellular Localization
Cell membrane; Single-pass type I membrane protein
SEMA6A Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SEMA6A antibody detected the SEMA6A protein (arrow).
Application Notes
WB:1:50~100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.