Application
SIRPG Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SIRPG antibody detected the SIRPG protein (arrow).| Product Name | SIRPG Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SIRPG; SIRPB2; Signal-regulatory protein gamma; CD172 antigen-like family member B; Signal-regulatory protein beta-2; CD_antigen=CD172g; Flags: Precursor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SIRPB2 |
|---|---|
| Alternative Names | SIRPG SIRPB2 Signal-regulatory protein gamma CD172 antigen-like family member B Signal-regulatory protein beta-2 CD_antigen=CD172g Flags: Precursor |
| Molecular Weight(MW) | 42498 Da |
| Function | Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T- cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation |
| Tissue Specificity | Detected in liver, and at very low levels in brain, heart, lung, pancreas, kidney, placenta and skeletal muscle. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. Mainly present in the paracortical T-cell area of lymph nodes, with only sparse positive cells in the mantle and in the germinal center of B-cell follicles. In the thymus, primarily expressed in the medulla on mature T-lymphocytes that have undergone thymic selection |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 55423 |
|---|---|
| Nucleotide Accession | NP_543006.2 NP_001034597.1 |
Application
SIRPG Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SIRPG antibody detected the SIRPG protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
