Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.1) Nyati, M.K., et al. Cancer Res. 66(24):11554-11559(2006)
Immunogen
This SIRPB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-255 amino acids from the C-terminal region of human SIRPB2.
Signal-regulatory protein beta-2 SIRP-beta-2 Protein tyrosine phosphatase non-receptor type substrate 1-like 3 Protein tyrosine phosphatase non-receptor type substrate protein SIRPB2 PTPN1L PTPNS1L3
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.