Application
A. Western blot analysis on fetal brain lysate using anti-Alpha-synuclein RabMAb (Cat. #AJ1033a), dilution 1:50,000.Application
B. Immunofluorescent staining of PC12 cells using anti-Alpha-Synuclein RabMAb (Cat. #AJ1033a).| Product Name | SNCA Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SNCA, NACP, PARK1, Alpha-synuclein, Non-A beta component of AD amyloid;Non-A4 component of amyloid precursor |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1646Y |
| Host Species | Rabbit |
| Tested Applications | WBIF |
| WB:1:1000~5000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NACP PARK1 |
|---|---|
| Alternative Names | SNCA NACP PARK1 Alpha-synuclein Non-A beta component of AD amyloid Non-A4 component of amyloid precursor |
| Molecular Weight(MW) | 14460 Da |
| Function | May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation |
| Tissue Specificity | Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals |
| Cellular Localization | Cytoplasm. Membrane. Nucleus. Cell junction, synapse. Note=Membrane-bound in dopaminergic neurons |
| Entrez Gene | 6622 |
|---|
Application
A. Western blot analysis on fetal brain lysate using anti-Alpha-synuclein RabMAb (Cat. #AJ1033a), dilution 1:50,000.
Application
B. Immunofluorescent staining of PC12 cells using anti-Alpha-Synuclein RabMAb (Cat. #AJ1033a).| Application Notes | WB:1:1000~5000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
