Application
Western blot analysis of SNCA Antibody (C-term) in mouse brain tissue lysates (35ug/lane). SNCA (arrow) was detected using the purified Pab.(4/6ug/ml)Application
SNCA Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SNCA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | SNCA Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SNCA; NACP; PARK1; Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NACP PARK1 |
|---|---|
| Alternative Names | SNCA NACP PARK1 Alpha-synuclein Non-A beta component of AD amyloid Non-A4 component of amyloid precursor |
| Molecular Weight(MW) | 14460 Da |
| Function | May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation |
| Tissue Specificity | Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals |
| Cellular Localization | Cytoplasm. Membrane. Nucleus. Cell junction, synapse. Note=Membrane-bound in dopaminergic neurons |
| Entrez Gene | 6622 |
|---|
Application
Western blot analysis of SNCA Antibody (C-term) in mouse brain tissue lysates (35ug/lane). SNCA (arrow) was detected using the purified Pab.(4/6ug/ml)
Application
SNCA Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SNCA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
