| Gene Summary |
Enables arachidonate binding activity; histone binding activity; and identical protein binding activity. Involved in several processes, including protein-containing complex assembly; regulation of reactive oxygen species metabolic process; and synaptic vesicle endocytosis. Acts upstream of or within several processes, including chemical synaptic transmission; modulation of chemical synaptic transmission; and regulation of amine transport. Located in several cellular components, including axon terminus; inclusion body; and neuronal cell body. Is active in synaptic vesicle membrane. Is expressed in several structures, including central nervous system; future brain; genitourinary system; sensory ganglion; and sensory organ. Used to study Parkinson's disease 1 and Parkinson's disease 4. Human ortholog(s) of this gene implicated in Alzheimer's disease; Lewy body dementia; Parkinson's disease; Parkinson's disease 1; and Parkinson's disease 4. Orthologous to human SNCA (synuclein alpha). [provided by Alliance of Genome Resources, Jul 2025] |