SNX6 Antibody (Cat. #AM1969a) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the SNX6 antibody detected the SNX6 protein (arrow).
May be involved in several stages of intracellular trafficking. Promotes lysosomal degradation of CDKN1B (By similarity). Plays a role in retrograde protein transport from endosomes to the trans-Golgi network. May function as link between transport vesicles and dynactin. Negatively regulates retrograde transport of BACE1 from the cell surface to the trans-Golgi network. May contribute to transcription regulation
Tissue Specificity
This SNX6 monoclonal antibody is generated from mouse immunized with SNX6 recombinant protein.
Cellular Localization
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Nucleus Note=Interaction with SNX1 or SNX2 promotes location at endosome membranes. Only a minor proportion is seen in the nucleus
SNX6 Antibody (Cat. #AM1969a) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the SNX6 antibody detected the SNX6 protein (arrow).
Application Notes
WB:1:1000~16000
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.