Application
SOCS4 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SOCS4 antibody detected the SOCS4 protein (arrow).| Product Name | SOCS4 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SOCS4; SOCS7; Suppressor of cytokine signaling 4; Suppressor of cytokine signaling 7 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SOCS7 |
|---|---|
| Alternative Names | SOCS4 SOCS7 Suppressor of cytokine signaling 4 Suppressor of cytokine signaling 7 |
| Molecular Weight(MW) | 50623 Da |
| Function | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction Substrate-recognition component of a SCF-like ECS (Elongin BC- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR |
| Tissue Specificity | This SOCS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-253 amino acids from the Central region of human SOCS4. |
| Entrez Gene | 122809 |
|---|---|
| Nucleotide Accession | NP_955453.1 NP_543143.1 |
Application
SOCS4 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SOCS4 antibody detected the SOCS4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
