Application
Figure 1: Western blot analysis using SOX2 monoclonal antibody against truncated Trx-SOX2 recombinant protein(1) and truncated MBP-SOX2(aa1-170) recombinant protein(2).| Product Name | SOX2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ANOP3; MCOPS3; MGC2413 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 10F10C9 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500 - 2000. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | ANOP3 MCOPS3 MGC2413 |
|---|---|
| Molecular Weight(MW) | 34310 Da |
| Function | Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity) |
| Tissue Specificity | Purified recombinant fragment of SOX2(aa1-170) expressed in E. Coli. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 6657 |
|---|---|
| Nucleotide Accession | NP_003097.1 |
Application
Figure 1: Western blot analysis using SOX2 monoclonal antibody against truncated Trx-SOX2 recombinant protein(1) and truncated MBP-SOX2(aa1-170) recombinant protein(2).| Application Notes | WB:1:500 - 2000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of SOX2(aa1-170) expressed in E. Coli. |
