Application
STAG1 Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the STAG1 antibody detected the STAG1 protein (arrow).| Product Name | STAG1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | STAG1; SA1; Cohesin subunit SA-1; SCC3 homolog 1; Stromal antigen 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SA1 |
|---|---|
| Alternative Names | STAG1 SA1 Cohesin subunit SA-1 SCC3 homolog 1 Stromal antigen 1 |
| Molecular Weight(MW) | 144427 Da |
| Function | Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis |
| Tissue Specificity | This STAG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-568 amino acids from the Central region of human STAG1. |
| Cellular Localization | Nucleus. Chromosome. Chromosome, centromere. Note=Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK1, except at centromeres, where cohesin complexes remain. At anaphase, the RAD21 subunit of cohesin is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation |
| Entrez Gene | 10274 |
|---|---|
| Nucleotide Accession | NP_005853.2 |
Application
STAG1 Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the STAG1 antibody detected the STAG1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
