Application
Figure 1: Western blot analysis using anti-SYT1 monoclonal antibody against truncated Trx-SYT1 recombinant protein(1).| Product Name | SYT1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | P65; SYT; SVP65; DKFZp781D2042 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 8G11B10 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500 - 2000. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SVP65 SYT |
|---|---|
| Alternative Names | P65 SYT SVP65 DKFZp781D2042 |
| Molecular Weight(MW) | 47573 Da |
| Function | May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2 |
| Tissue Specificity | Purified recombinant fragment of SYT1 expressed in E. Coli. |
| Cellular Localization | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass membrane protein. Cytoplasm. Note=Synaptic vesicles and chromaffin granules |
| Entrez Gene | 6857 |
|---|---|
| Nucleotide Accession | NP_005630.1 |
Application
Figure 1: Western blot analysis using anti-SYT1 monoclonal antibody against truncated Trx-SYT1 recombinant protein(1).| Application Notes | WB:1:500 - 2000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of SYT1 expressed in E. Coli. |
