Application
SYUG Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SYUG antibody detected the SYUG protein (arrow).Application
SYUG Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SYUG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
Confocal immunofluorescent analysis of SYUG Antibody (C-term)(Cat#AP11775b) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).Application
SYUG Antibody (C-term) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | SYUG Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SNCG; BCSG1; PERSYN; PRSN; Gamma-synuclein; Breast cancer-specific gene 1 protein; Persyn; Synoretin |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCIFFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BCSG1 PERSYN PRSN |
|---|---|
| Alternative Names | SNCG BCSG1 PERSYN PRSN Gamma-synuclein Breast cancer-specific gene 1 protein Persyn Synoretin |
| Molecular Weight(MW) | 13331 Da |
| Function | Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity) May also function in modulating the keratin network in skin Activates the MAPK and Elk-1 signal transduction pathway (By similarity) |
| Tissue Specificity | Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung |
| Cellular Localization | Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle |
| Entrez Gene | 6623 |
|---|---|
| Nucleotide Accession | NP_003078.2 |
Application
SYUG Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SYUG antibody detected the SYUG protein (arrow).
Application
SYUG Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SYUG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
Confocal immunofluorescent analysis of SYUG Antibody (C-term)(Cat#AP11775b) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Application
SYUG Antibody (C-term) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
