Application
Figure 1: Western blot analysis using anti-SNCG monoclonal antiobdy against truncated SNCG recombinant protein.Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma(left) and breast carcinoma(right), showing cytoplasmic(ovary carcinoma) localization, cytoplasmic and nuclear(breast carcinoma) localization using anti-SNCG antibody with DAB staining.| Product Name | SNCG Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SR; BCSG1 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 1H10D2 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500 - 2000. IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BCSG1 PERSYN PRSN |
|---|---|
| Alternative Names | SR BCSG1 |
| Molecular Weight(MW) | 13331 Da |
| Function | Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity) May also function in modulating the keratin network in skin Activates the MAPK and Elk-1 signal transduction pathway (By similarity) |
| Tissue Specificity | Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung |
| Cellular Localization | Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle |
| Entrez Gene | 6623 |
|---|---|
| Nucleotide Accession | NP_003078.2 |
Application
Figure 1: Western blot analysis using anti-SNCG monoclonal antiobdy against truncated SNCG recombinant protein.
Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma(left) and breast carcinoma(right), showing cytoplasmic(ovary carcinoma) localization, cytoplasmic and nuclear(breast carcinoma) localization using anti-SNCG antibody with DAB staining.| Application Notes | WB:1:500 - 2000. IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of SNCG expressed in E. Coli. |
