Application
TAOK3 Antibody (Cat. #AM1859a) western blot analysis in K562 cell line lysates (15ug/lane).This demonstrates the TAOK3 antibody detected the TAOK3 protein (arrow).(1:8000)| Product Name | TAOK3 Antibody (Ascites) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TAOK3; DPK; JIK; KDS; MAP3K18; Serine/threonine-protein kinase TAO3; Cutaneous T-cell lymphoma-associated antigen HD-CL-09; Dendritic cell-derived protein kinase; JNK/SAPK-inhibitory kinase; Jun kinase-inhibitory kinase; Kinase from chicken homolog A; Thou |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 173CT19.6.2 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:8000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DPK JIK KDS MAP3K18 |
|---|---|
| Alternative Names | TAOK3 DPK JIK KDS MAP3K18 Serine/threonine-protein kinase TAO3 Cutaneous T-cell lymphoma-associated antigen HD-CL-09 Dendritic cell-derived protein kinase JNK/SAPK-inhibitory kinase Jun kinase-inhibitory kinase Kinase from chicken homolog A Thou |
| Molecular Weight(MW) | 105406 Da |
| Function | Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress- activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF) |
| Tissue Specificity | Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver |
| Cellular Localization | Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also localized to the peripheral cell membrane |
| Entrez Gene | 51347 |
|---|---|
| Nucleotide Accession | NP_057365.3 |
Application
TAOK3 Antibody (Cat. #AM1859a) western blot analysis in K562 cell line lysates (15ug/lane).This demonstrates the TAOK3 antibody detected the TAOK3 protein (arrow).(1:8000)| Application Notes | WB:1:8000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
