RHOQ, ARHQ, RASL7A, TC10, Rho-related GTP-binding protein RhoQ, Ras-related GTP-binding protein TC10;Ras-like protein family member 7A
Key Feature
Clonality
Monoclonal
Clone Number
Y304
Host Species
Rabbit
Tested Applications
WBIF
WB:1:1000~10000
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
ARHQ RASL7A TC10
Alternative Names
RHOQ ARHQ RASL7A TC10 Rho-related GTP-binding protein RhoQ Ras-related GTP-binding protein TC10 Ras-like protein family member 7A
Molecular Weight(MW)
22659 Da
Function
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia
Tissue Specificity
A synthetic peptide corresponding to the third GTP unit of human TC10 was used as immunogen.