Application
TC10 Antibody (Center) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the TC10 antibody detected the TC10 protein (arrow).Application
TC10 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TC10 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | TC10 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RHOQ; ARHQ; RASL7A; TC10; Rho-related GTP-binding protein RhoQ; Ras-like protein TC10; Ras-like protein family member 7A |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ARHQ RASL7A TC10 |
|---|---|
| Alternative Names | RHOQ ARHQ RASL7A TC10 Rho-related GTP-binding protein RhoQ Ras-like protein TC10 Ras-like protein family member 7A |
| Molecular Weight(MW) | 22659 Da |
| Function | Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia |
| Tissue Specificity | This TC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the Central region of human TC10. |
| Cellular Localization | Cytoplasm. Cell membrane; Lipid-anchor. |
| Entrez Gene | 23433 |
|---|---|
| Nucleotide Accession | NP_036381.2 |
Application
TC10 Antibody (Center) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the TC10 antibody detected the TC10 protein (arrow).
Application
TC10 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TC10 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
