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TGF beta1 Antibody

Catalog Number:OM222871
OM222871
Discount Price
OM222871-100ul
1~2 Week
100ul
OM222871-50ul
50ul
1~2 Week
Product Profile
Product Name TGF beta1 Antibody
Antibody Type Primary Antibodies
Key Feature
Clonality Monoclonal
Isotype IgG2a
Clone Number 4F9C10,1B11B7
Host Species Mouse
Tested Applications ICC/IFIHCWB
WB:1:500 - 2000.
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms TGFB
Alternative Names CED
DPD1
TGFB
TGFbeta
TGFB1
Molecular Weight(MW) 44341 Da
Function Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts
Tissue Specificity Highly expressed in bone. Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA). Co-localizes with ASPN in chondrocytes within OA lesions of articular cartilage
Cellular Localization Secreted, extracellular space, extracellular matrix
Database Links
Entrez Gene 7040
Nucleotide Accession NP_000651.3
Application

Application

Figure 1: Western blot analysis using anti-TGF beta1 monoclonal antiobdy against truncated TGF beta1 recombinant protein.
Application Notes WB:1:500 - 2000.
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified recombinant fragment of TGFbeta1 expressed in E. Coli.
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