TGIF1 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TGIF1 antibody detected the TGIF1 protein (arrow).
TGIF1 TGIF Homeobox protein TGIF1 5'-TG-3'-interacting factor 1
Molecular Weight(MW)
43013 Da
Function
Binds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter (CRBPII- RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element Active transcriptional corepressor of SMAD2. Links the nodal signaling pathway to the bifurcation of the forebrain and the establishment of ventral midline structures. May participate in the transmission of nuclear signals during development and in the adult, as illustrated by the down-modulation of the RXR alpha activities
Tissue Specificity
This TGIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-109 amino acids from the N-terminal region of human TGIF1.
TGIF1 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TGIF1 antibody detected the TGIF1 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.