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TGIF Antibody (C-term)

Catalog Number:OM222894
OM222894
Discount Price
OM222894-100ul
1~2 Week
100ul
OM222894-50ul
50ul
OM222894-20ul
20ul
1~2 Week
Product Profile
Product Name TGIF Antibody (C-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Monoclonal
Clone Number EP637Y
Host Species Rabbit
Tested Applications WB
WB:1:1000
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms TGIF
Alternative Names TGIF1
TGIF
Homeobox protein TGIF1
5'-TG-3'-interacting factor 1
Molecular Weight(MW) 43013 Da
Function Binds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter (CRBPII- RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element Active transcriptional corepressor of SMAD2. Links the nodal signaling pathway to the bifurcation of the forebrain and the establishment of ventral midline structures. May participate in the transmission of nuclear signals during development and in the adult, as illustrated by the down-modulation of the RXR alpha activities
Tissue Specificity A synthetic peptide corresponding to residues on the C-terminus of human TGIF was used as an immunogen. This antibody detects both phosphorylated and unphosphorylated TGIF.
Cellular Localization Nucleus.
Database Links
Entrez Gene 7050
Application

Application

A. Western blot analysis on K562 cell lysate using anti-TGIF RabMAb (Cat. #AJ1766a), dilution 1:1000.
Application Notes WB:1:1000
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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