Application
Figure 1: Western blot analysis using anti-TIMP3 polyclonal antiobdy against truncated TIMP3 recombinant protein.Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma(left) and breast carcinoma(right), showing cytoplasmic localization using anti-TIMP3 polyclonal antibody with DAB staining.| Product Name | TIMP-3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500 - 2000. IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SFD K222 K222TA2 HSMRK222 |
|---|---|
| Molecular Weight(MW) | 24145 Da |
| Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15 |
| Tissue Specificity | Purified recombinant fragment of human TIMP-3 expressed in E. Coli. |
| Cellular Localization | Secreted, extracellular space, extracellular matrix |
| Entrez Gene | 7078 |
|---|---|
| Nucleotide Accession | NP_000353.1 |
Application
Figure 1: Western blot analysis using anti-TIMP3 polyclonal antiobdy against truncated TIMP3 recombinant protein.
Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma(left) and breast carcinoma(right), showing cytoplasmic localization using anti-TIMP3 polyclonal antibody with DAB staining.| Application Notes | WB:1:500 - 2000. IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human TIMP-3 expressed in E. Coli. |
