Application
TNK1 Antibody (Cat. #AM1861a) western blot analysis in mouse brain cell line lysates (15ug/lane).This demonstrates the TNK1 antibody detected the TNK1 protein (arrow).(1:500)Application
TNK1 Monoclonal( Ascites) (Cat. #AM1861a) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TNK1 Monoclonal( Ascites) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | TNK1 Antibody (Ascites) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNK1; Non-receptor tyrosine-protein kinase TNK1; CD38 negative kinase 1 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 170CT7.5.4 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TNK1 Non-receptor tyrosine-protein kinase TNK1 CD38 negative kinase 1 |
|---|---|
| Molecular Weight(MW) | 72468 Da |
| Function | Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction |
| Tissue Specificity | Expressed in all umbilical cord blood, bone marrow and adult blood cell sub-populations and in several leukemia cell lines. Highly expressed in fetal blood, brain, lung, liver and kidney. Detected at lower levels in adult prostate, testis, ovary, small intestine and colon. Not expressed in adult lung, liver, kidney or brain |
| Cellular Localization | Cytoplasm. Membrane; Peripheral membrane protein |
| Entrez Gene | 8711 |
|---|---|
| Nucleotide Accession | NP_003976.2 |
Application
TNK1 Antibody (Cat. #AM1861a) western blot analysis in mouse brain cell line lysates (15ug/lane).This demonstrates the TNK1 antibody detected the TNK1 protein (arrow).(1:500)
Application
TNK1 Monoclonal( Ascites) (Cat. #AM1861a) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TNK1 Monoclonal( Ascites) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
