Application
TNK1 Antibody (Cat. #AM1861b) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the TNK1 antibody detected the TNK1 protein (arrow).| Product Name | TNK1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNK1; Non-receptor tyrosine-protein kinase TNK1; CD38 negative kinase 1 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 170CT7.5.4 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:100~1000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TNK1 Non-receptor tyrosine-protein kinase TNK1 CD38 negative kinase 1 |
|---|---|
| Molecular Weight(MW) | 72468 Da |
| Function | Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction |
| Tissue Specificity | Expressed in all umbilical cord blood, bone marrow and adult blood cell sub-populations and in several leukemia cell lines. Highly expressed in fetal blood, brain, lung, liver and kidney. Detected at lower levels in adult prostate, testis, ovary, small intestine and colon. Not expressed in adult lung, liver, kidney or brain |
| Cellular Localization | Cytoplasm. Membrane; Peripheral membrane protein |
| Entrez Gene | 8711 |
|---|---|
| Nucleotide Accession | NP_003976.2 |
Application
TNK1 Antibody (Cat. #AM1861b) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the TNK1 antibody detected the TNK1 protein (arrow).| Application Notes | WB:1:100~1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
