Application
Figure 1: Western blot analysis using anti-TNK1 monoclonal antibody against truncated TNK1-His recombinant protein(1).| Product Name | TNK1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MGC46193; TNK1 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 1B5G3;3F11H6 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500 - 2000. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | MGC46193 TNK1 |
|---|---|
| Molecular Weight(MW) | 72468 Da |
| Function | Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction |
| Tissue Specificity | Expressed in all umbilical cord blood, bone marrow and adult blood cell sub-populations and in several leukemia cell lines. Highly expressed in fetal blood, brain, lung, liver and kidney. Detected at lower levels in adult prostate, testis, ovary, small intestine and colon. Not expressed in adult lung, liver, kidney or brain |
| Cellular Localization | Cytoplasm. Membrane; Peripheral membrane protein |
| Entrez Gene | 8711 |
|---|---|
| Nucleotide Accession | NP_003976.2 |
Application
Figure 1: Western blot analysis using anti-TNK1 monoclonal antibody against truncated TNK1-His recombinant protein(1).| Application Notes | WB:1:500 - 2000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of TNK1(aa451-560) expressed in E. Coli. |
