Application
TXN Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TXN antibody detected the TXN protein (arrow).| Product Name | TXN Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TXN;TRDX; TRX; TRX1; Thioredoxin; Thioredoxin; ATL-derived factor; Thioredoxin; Surface-associated sulphydryl protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TRDX TRX TRX1 |
|---|---|
| Alternative Names | TXN TRDX TRX TRX1 Thioredoxin Thioredoxin ATL-derived factor Thioredoxin Surface-associated sulphydryl protein |
| Molecular Weight(MW) | 11737 Da |
| Function | Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity |
| Tissue Specificity | This TXN Antibody Antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the C-term region of human TXN. |
| Cellular Localization | Nucleus. Cytoplasm. Secreted. Note=Secreted by a leaderless secretory pathway. Predominantly in the cytoplasm in non irradiated cells. Radiation induces translocation of TRX from the cytoplasm to the nucleus |
| Entrez Gene | 7295 |
|---|
Application
TXN Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TXN antibody detected the TXN protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
