Application
UBA2 Antibody (M1) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the UBA2 antibody detected the UBA2 protein (arrow).Application
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with UBA2 Antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.Application
UBA2 Antibody (M1) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UBA2 antibody detected the UBA2 protein (arrow).| Product Name | UBA2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UBA2; SAE2; UBLE1B; SUMO-activating enzyme subunit 2; Anthracycline-associated resistance ARX; Ubiquitin-like 1-activating enzyme E1B |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SAE2 UBLE1B |
|---|---|
| Alternative Names | UBA2 SAE2 UBLE1B SUMO-activating enzyme subunit 2 Anthracycline-associated resistance ARX Ubiquitin-like 1-activating enzyme E1B |
| Molecular Weight(MW) | 71224 Da |
| Function | The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2 |
| Tissue Specificity | This UBA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human UBA2. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 10054 |
|---|
Application
UBA2 Antibody (M1) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the UBA2 antibody detected the UBA2 protein (arrow).
Application
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with UBA2 Antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application
UBA2 Antibody (M1) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UBA2 antibody detected the UBA2 protein (arrow).| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
