Application
Figure 1: Western blot analysis using VCAM1 mouse mAb against HUVEC (1) and EC (2) cell lysate.Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human lung cancer (A) and colon cancer (B) using VCAM1 mouse mAb with DAB staining.| Product Name | VCAM1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 6G9 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500 - 2000. IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | L1CAM |
|---|---|
| Alternative Names | CD106 MGC99561 INCAM-100 DKFZp779G2333 VCAM1 |
| Molecular Weight(MW) | 81276 Da |
| Function | Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation |
| Tissue Specificity | Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 7412 |
|---|---|
| Nucleotide Accession | NP_542413.1 |
Application
Figure 1: Western blot analysis using VCAM1 mouse mAb against HUVEC (1) and EC (2) cell lysate.
Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human lung cancer (A) and colon cancer (B) using VCAM1 mouse mAb with DAB staining.| Application Notes | WB:1:500 - 2000. IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human VCAM1 expressed in E. Coli. |
