Application
WAS Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the WAS antibody detected the WAS protein (arrow).| Product Name | WAS (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | WAS; IMD2; Wiskott-Aldrich syndrome protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IMD2 |
|---|---|
| Alternative Names | WAS IMD2 Wiskott-Aldrich syndrome protein |
| Molecular Weight(MW) | 52913 Da |
| Function | Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria |
| Tissue Specificity | Expressed predominantly in the thymus. Also found, to a much lesser extent, in the spleen |
| Cellular Localization | Cytoplasm, cytoskeleton. |
| Entrez Gene | 7454 |
|---|---|
| Nucleotide Accession | NP_000368.1 |
Application
WAS Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the WAS antibody detected the WAS protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
