Application
A. Western blot analysis on (A) TF-1 and (B) U937 cell lysate using anti-WASP RabMAb (Cat. #AJ1819b), dilution 1:50,000.Application
B. Immunohistochemical analysis ofparaffin-embedded human spleen using anti-WASP RabMAb (Cat. #AJ1819b).| Product Name | WASP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | WAS, IMD2, Wiskott-Aldrich syndrome protein |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP2541Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:10000~50000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IMD2 |
|---|---|
| Alternative Names | WAS IMD2 Wiskott-Aldrich syndrome protein |
| Molecular Weight(MW) | 52913 Da |
| Function | Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria |
| Tissue Specificity | Expressed predominantly in the thymus. Also found, to a much lesser extent, in the spleen |
| Cellular Localization | Cytoplasm, cytoskeleton. |
| Entrez Gene | 7454 |
|---|
Application
A. Western blot analysis on (A) TF-1 and (B) U937 cell lysate using anti-WASP RabMAb (Cat. #AJ1819b), dilution 1:50,000.
Application
B. Immunohistochemical analysis ofparaffin-embedded human spleen using anti-WASP RabMAb (Cat. #AJ1819b).| Application Notes | WB:1:10000~50000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
