Application
A. Western blot analysis on (A) U937 (B) human small intestine (C) human liver lysate using anti-ACAT RabMAb (Cat. #AJ1008b), dilution 1:50,000.| Product Name | ACAT Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CES1, CES2, SES1, Liver carboxylesterase 1, Egasyn;Retinyl ester hydrolase |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1375Y |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:25000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CES2 SES1 |
|---|---|
| Alternative Names | CES1 CES2 SES1 Liver carboxylesterase 1 Egasyn Retinyl ester hydrolase |
| Molecular Weight(MW) | 62521 Da |
| Function | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate |
| Tissue Specificity | Expressed predominantly in liver with lower levels in heart and lung |
| Cellular Localization | Endoplasmic reticulum lumen. |
| Entrez Gene | 1066 |
|---|
Application
A. Western blot analysis on (A) U937 (B) human small intestine (C) human liver lysate using anti-ACAT RabMAb (Cat. #AJ1008b), dilution 1:50,000.| Application Notes | WB:1:25000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
