Application
CES1 Antibody (C-term) western blot analysis in HepG2,Sk-Br-3 cell line and mouse kidney tissue lysates (35ug/lane).This demonstrates the CES1 antibody detected the CES1 protein (arrow).Application
CES1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CES1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | CES1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CES1; CES2; SES1; Liver carboxylesterase 1; Acyl-coenzyme A:cholesterol acyltransferase; Brain carboxylesterase hBr1; Carboxylesterase 1; Cocaine carboxylesterase; Egasyn; HMSE; Methylumbelliferyl-acetate deacetylase 1; Monocyte/macrophage serine esterase; |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CES2 SES1 |
|---|---|
| Alternative Names | CES1 CES2 SES1 Liver carboxylesterase 1 Acyl-coenzyme A:cholesterol acyltransferase Brain carboxylesterase hBr1 Carboxylesterase 1 Cocaine carboxylesterase Egasyn HMSE Methylumbelliferyl-acetate deacetylase 1 Monocyte/macrophage serine esterase |
| Molecular Weight(MW) | 62521 Da |
| Function | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate |
| Tissue Specificity | Expressed predominantly in liver with lower levels in heart and lung |
| Cellular Localization | Endoplasmic reticulum lumen. |
| Entrez Gene | 1066 |
|---|
Application
CES1 Antibody (C-term) western blot analysis in HepG2,Sk-Br-3 cell line and mouse kidney tissue lysates (35ug/lane).This demonstrates the CES1 antibody detected the CES1 protein (arrow).
Application
CES1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CES1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
