Application
ACE2 Antibody (Cat. #AM2197b) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the ACE2 antibody detected the ACE2 protein (arrow).| Product Name | ACE2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ACE2;Angiotensin-converting enzyme 2; Angiotensin-converting enzyme 2; ACE-related carboxypeptidase; Angiotensin-converting enzyme 2; Angiotensin-converting enzyme homolog; Angiotensin-converting enzyme 2; Metalloprotease MPROT15; Processed angiotensin-con |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM |
| Clone Number | 881CT16.4.4 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:1000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | ACE2 Angiotensin-converting enzyme 2 Angiotensin-converting enzyme 2 ACE-related carboxypeptidase Angiotensin-converting enzyme 2 Angiotensin-converting enzyme homolog Angiotensin-converting enzyme 2 Metalloprotease MPROT15 Processed angiotensin-con |
|---|---|
| Molecular Weight(MW) | 92463 Da |
| Function | Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin- 13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses |
| Tissue Specificity | Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level) Expressed in heart, kidney, testis, and gastrointestinal system |
| Cellular Localization | Processed angiotensin-converting enzyme 2: Secreted |
| Entrez Gene | 59272 |
|---|
Application
ACE2 Antibody (Cat. #AM2197b) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the ACE2 antibody detected the ACE2 protein (arrow).| Application Notes | WB:1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS. |
