Application
ADA Antibody (C-term)(Cat. #AM2128b) western blot analysis in CEM,Jurkat cell line lysates (35ug/lane).This demonstrates the ADA antibody detected the ADA protein (arrow).| Product Name | ADA Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADA; ADA1; Adenosine deaminase; Adenosine aminohydrolase |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 608CT2.1.3 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:100~250 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ADA1 |
|---|---|
| Alternative Names | ADA ADA1 Adenosine deaminase Adenosine aminohydrolase |
| Molecular Weight(MW) | 40764 Da |
| Function | Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte- epithelial cell adhesion |
| Tissue Specificity | Found in all tissues, occurs in large amounts in T-lymphocytes and, at the time of weaning, in gastrointestinal tissues |
| Cellular Localization | Cell membrane; Peripheral membrane protein; Extracellular side. Cell junction. Cytoplasmic vesicle lumen (By similarity). Cytoplasm (By similarity). Note=Colocalized with DPP4 at the cell junction in lymphocyte-epithelial cell adhesion |
| Entrez Gene | 100 |
|---|---|
| Nucleotide Accession | NP_000013.2 |
Application
ADA Antibody (C-term)(Cat. #AM2128b) western blot analysis in CEM,Jurkat cell line lysates (35ug/lane).This demonstrates the ADA antibody detected the ADA protein (arrow).| Application Notes | WB:1:100~250 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
