Application
AIF1 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the AIF1 antibody detected the AIF1 protein (arrow).Application
AIF1 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AIF1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | AIF1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | G1, IBA1 |
|---|---|
| Alternative Names | AIF1 G1 IBA1 Allograft inflammatory factor 1 Ionized calcium-binding adapter molecule 1 Protein G1 |
| Molecular Weight(MW) | 16703 Da |
| Function | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1 Binds calcium. Plays a role in RAC signaling and in phagocytosis May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation |
| Tissue Specificity | Detected in T-lymphocytes and peripheral blood mononuclear cells |
| Cellular Localization | Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis |
| Entrez Gene | 199 |
|---|---|
| Nucleotide Accession | NP_001614.3 |
Application
AIF1 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the AIF1 antibody detected the AIF1 protein (arrow).
Application
AIF1 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AIF1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
