Application
AKR1C1 Antibody (C-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the AKR1C1 antibody detected the AKR1C1 protein (arrow).Application
AKR1C1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AKR1C1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | AKR1C1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DDH, DDH1 |
|---|---|
| Alternative Names | AKR1C1 DDH DDH1 Aldo-keto reductase family 1 member C1 20-alpha-hydroxysteroid dehydrogenase Chlordecone reductase homolog HAKRC Dihydrodiol dehydrogenase 1/2 High-affinity hepatic bile acid-binding protein Indanol dehydrogenase Trans-1 2-dihydro |
| Molecular Weight(MW) | 36788 Da |
| Function | Converts progesterone to its inactive form, 20-alpha- dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation |
| Tissue Specificity | Expressed in all tissues tested including liver, prostate, testis, adrenal gland, brain, uterus, mammary gland and keratinocytes. Highest levels found in liver, mammary gland and brain |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 1645 |
|---|---|
| Nucleotide Accession | NP_001344.2 |
Application
AKR1C1 Antibody (C-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the AKR1C1 antibody detected the AKR1C1 protein (arrow).
Application
AKR1C1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AKR1C1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
