Application
Figure 1: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma(A), kidney carcinoma(B), lung carcinoma(C) and breast carcinoma(D), showing cytoplasmic and membrane localization with DAB staining using anti-ALCAM Antibody.| Product Name | ALCAM Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 10F1G12 |
| Host Species | Mouse |
| Tested Applications | IHC |
| IHC:1:200 - 1000. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MEMD |
|---|---|
| Alternative Names | MEMD CD166 ALCAM |
| Molecular Weight(MW) | 65102 Da |
| Function | Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system |
| Tissue Specificity | Spleen, placenta, liver, and weakly in liver. Expressed by activated T-cells, B-cells, monocytes and thymic epithelial cells. Expressed by neurons in the brain. Restricted expression in tumor cell lines. Preferentially expressed in highly metastasizing melanoma cell lines |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 214 |
|---|---|
| Nucleotide Accession | NP_001618.2 |
Application
Figure 1: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma(A), kidney carcinoma(B), lung carcinoma(C) and breast carcinoma(D), showing cytoplasmic and membrane localization with DAB staining using anti-ALCAM Antibody.| Application Notes | IHC:1:200 - 1000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of ALCAM(aa405-524) expressed in E. Coli. |
