Application
Western blot analysis of anti-ALOX5AP Antibody (Center) in K562 cell line lysates (35ug/lane). ALOX5AP(arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ALOX5AP antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | ALOX5AP Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ALOX5AP; FLAP; Arachidonate 5-lipoxygenase-activating protein; MK-886-binding protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FLAP |
|---|---|
| Alternative Names | ALOX5AP FLAP Arachidonate 5-lipoxygenase-activating protein MK-886-binding protein |
| Molecular Weight(MW) | 18157 Da |
| Function | Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes |
| Tissue Specificity | This ALOX5AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94~124 amino acids from the Center region of human ALOX5AP. |
| Cellular Localization | Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Entrez Gene | 241 |
|---|
Application
Western blot analysis of anti-ALOX5AP Antibody (Center) in K562 cell line lysates (35ug/lane). ALOX5AP(arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ALOX5AP antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
