Application
ANAPC1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ANAPC1 antibody detected the ANAPC1 protein (arrow).Application
ANAPC1 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ANAPC1 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | ANAPC1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ANAPC1; TSG24; Anaphase-promoting complex subunit 1; Cyclosome subunit 1; Mitotic checkpoint regulator; Testis-specific gene 24 protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TSG24 |
|---|---|
| Alternative Names | ANAPC1 TSG24 Anaphase-promoting complex subunit 1 Cyclosome subunit 1 Mitotic checkpoint regulator Testis-specific gene 24 protein |
| Molecular Weight(MW) | 216500 Da |
| Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains |
| Tissue Specificity | This ANAPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 698-728 amino acids from the Central region of human ANAPC1. |
| Entrez Gene | 64682 |
|---|---|
| Nucleotide Accession | NP_073153.1 |
Application
ANAPC1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ANAPC1 antibody detected the ANAPC1 protein (arrow).
Application
ANAPC1 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ANAPC1 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
