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Annexin A1 Antibody (Center)

Catalog Number:OM226518
OM226518
Discount Price
OM226518-100ul
1~2 Week
100ul
OM226518-50ul
50ul
OM226518-20ul
20ul
1~2 Week
Product Profile
Product Name Annexin A1 Antibody (Center)
Antibody Type Primary Antibodies
Antigen Alias ANXA1; ANX1; LPC1; Annexin A1; Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; Phospholipase A2 inhibitory protein; p35
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:50~100 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms ANX1
LPC1
Alternative Names ANXA1
ANX1
LPC1
Annexin A1
Annexin I
Annexin-1
Calpactin II
Calpactin-2
Chromobindin-9
Lipocortin I
Phospholipase A2 inhibitory protein
p35
Molecular Weight(MW) 38714 Da
Function Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity
Tissue Specificity This Annexin A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136~166 amino acids from the Center region of human Annexin A1.
Cellular Localization Nucleus (By similarity). Cytoplasm (By similarity). Cell projection, cilium (By similarity). Basolateral cell membrane (By similarity). Note=Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages (By similarity)
Database Links
Entrez Gene 301
Application

Application

Western blot analysis of Annexin A1 antibody (Center) in A2058 cell line lysates (35ug/lane). Annexin A1 (arrow) was detected using the purified Pab.

Application

Annexin A1 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the Annexin A1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

Annexin A1 Antibody (Center) flow cytometric analysis of A2058 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:50~100 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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