Application
ANP32A Antibody (C-term) western blot analysis in K562,CEM,HL-60 cell line lysates (35ug/lane).This demonstrates the ANP32A antibody detected the ANP32A protein (arrow).Application
Formalin-fixed and paraffin-embedded human skeletal muscle reacted with ANP32A Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | ANP32A Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ANP32A; C15orf1; LANP; MAPM; PHAP1; Acidic leucine-rich nuclear phosphoprotein 32 family member A; Acidic nuclear phosphoprotein pp32; Leucine-rich acidic nuclear protein; Mapmodulin; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; Putative HLA |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C15orf1 LANP MAPM PHAP1 |
|---|---|
| Alternative Names | ANP32A C15orf1 LANP MAPM PHAP1 Acidic leucine-rich nuclear phosphoprotein 32 family member A Acidic nuclear phosphoprotein pp32 Leucine-rich acidic nuclear protein Mapmodulin Potent heat-stable protein phosphatase 2A inhibitor I1PP2A Putative HLA |
| Molecular Weight(MW) | 28585 Da |
| Function | Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1- mediated transcriptional repression |
| Tissue Specificity | Expressed in all tissues tested. Highly expressed in kidney and skeletal muscle, moderate levels of expression in brain, placenta and pancreas, and weakly expressed in lung. Found in all regions of the brain examined (amygdala, caudate nucleus, corpus callosum, hippocampus and thalamus), with highest levels in amygdala |
| Cellular Localization | Nucleus. Cytoplasm. Endoplasmic reticulum. Note=Translocates to the cytoplasm during the process of neuritogenesis (By similarity). Shuttles between nucleus and cytoplasm |
| Entrez Gene | 8125 |
|---|
Application
ANP32A Antibody (C-term) western blot analysis in K562,CEM,HL-60 cell line lysates (35ug/lane).This demonstrates the ANP32A antibody detected the ANP32A protein (arrow).
Application
Formalin-fixed and paraffin-embedded human skeletal muscle reacted with ANP32A Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
