Application
Western blot analysis of anti-ANTXR1 Antibody (Y382) in Hela cell line lysates (35ug/lane). ANTXR1 (arrow) was detected using the purified Pab (1:60dilution).Application
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ANTXR1 Antibody (Y382) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | ANTXR1 Antibody (Y382) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ANTXR1; ATR; TEM8; Anthrax toxin receptor 1; Tumor endothelial marker 8 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ATR TEM8 |
|---|---|
| Alternative Names | ANTXR1 ATR TEM8 Anthrax toxin receptor 1 Tumor endothelial marker 8 |
| Molecular Weight(MW) | 62789 Da |
| Function | Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells |
| Tissue Specificity | Detected in umbilical vein endothelial cells (at protein level). Highly expressed in tumor endothelial cells |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. Cell projection, lamellipodium membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single- pass type I membrane protein. Note=At the membrane of lamellipodia and at the tip of actin-enriched filopodia. Colocalizes with actin at the base of lamellipodia |
| Entrez Gene | 84168 |
|---|
Application
Western blot analysis of anti-ANTXR1 Antibody (Y382) in Hela cell line lysates (35ug/lane). ANTXR1 (arrow) was detected using the purified Pab (1:60dilution).
Application
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ANTXR1 Antibody (Y382) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
