Application
Figure 1: Western blot analysis using anti-human APOA1 mAb against HepG2 cell lysate (1) and human serum (2).| Product Name | APOA1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MGC117399 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 5F4F5 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500 - 2000. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | MGC117399 |
|---|---|
| Molecular Weight(MW) | 30778 Da |
| Function | Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility |
| Tissue Specificity | Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease |
| Cellular Localization | Secreted. |
| Entrez Gene | 335 |
|---|---|
| Nucleotide Accession | NP_000030.1 |
Application
Figure 1: Western blot analysis using anti-human APOA1 mAb against HepG2 cell lysate (1) and human serum (2).| Application Notes | WB:1:500 - 2000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human APOA1 expressed in E. Coli. |
