Application
APOA1 Antibody (N-term) (Cat. #AM2045b) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the APOA1 antibody detected the APOA1 protein (arrow).| Product Name | APOA1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APOA1; Apolipoprotein A-I; Apolipoprotein A1; Truncated apolipoprotein A-I; Apolipoprotein A-I(1-242) |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 464CT10.4.4 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:100~250 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | APOA1 Apolipoprotein A-I Apolipoprotein A1 Truncated apolipoprotein A-I Apolipoprotein A-I(1-242) |
|---|---|
| Molecular Weight(MW) | 30778 Da |
| Function | Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility |
| Tissue Specificity | Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease |
| Cellular Localization | Secreted. |
| Entrez Gene | 335 |
|---|---|
| Nucleotide Accession | NP_000030.1 |
Application
APOA1 Antibody (N-term) (Cat. #AM2045b) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the APOA1 antibody detected the APOA1 protein (arrow).| Application Notes | WB:1:100~250 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
