Application
APOE antibody (Cat. #AM1876a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the APOE antibody detected the APOE protein (arrow).Application
APOE Antibody (Center) (Cat. #AM1876a) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the APOE Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | APOE antibody ( Ascites) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APOE; Apolipoprotein E |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG3 |
| Clone Number | 141CT76.16.6 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:1000~8000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | APOE Apolipoprotein E |
|---|---|
| Molecular Weight(MW) | 36154 Da |
| Function | Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues |
| Tissue Specificity | Occurs in all lipoprotein fractions in plasma. It constitutes 10-20% of very low density lipoproteins (VLDL) and 1-2% of high density lipoproteins (HDL). APOE is produced in most organs. Significant quantities are produced in liver, brain, spleen, lung, adrenal, ovary, kidney and muscle |
| Cellular Localization | Secreted. |
| Entrez Gene | 348 |
|---|---|
| Nucleotide Accession | NP_000032.1 |
Application
APOE antibody (Cat. #AM1876a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the APOE antibody detected the APOE protein (arrow).
Application
APOE Antibody (Center) (Cat. #AM1876a) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the APOE Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:1000~8000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
