Application
Western blot analysis of APPL1 Antibody (C-term) in mouse cerebellum tissue lysates (35ug/lane). APPL1 (arrow) was detected using the purified Pab.Application
APPL1 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the APPL1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
APPL1 Antibody (C-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | APPL1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APPL1; APPL; DIP13A; KIAA1428; DCC-interacting protein 13-alpha; Adapter protein containing PH domain, PTB domain and leucine zipper motif 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | APPL DIP13A KIAA1428 |
|---|---|
| Alternative Names | APPL1 APPL DIP13A KIAA1428 DCC-interacting protein 13-alpha Adapter protein containing PH domain PTB domain and leucine zipper motif 1 |
| Molecular Weight(MW) | 79663 Da |
| Function | Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction |
| Tissue Specificity | High levels in heart, ovary, pancreas and skeletal muscle |
| Cellular Localization | Early endosome membrane; Peripheral membrane protein. Nucleus. Note=Early endosomal membrane-bound and nuclear Translocated into the nucleus upon release from endosomal membranes following internalization of EGF |
| Entrez Gene | 26060 |
|---|
Application
Western blot analysis of APPL1 Antibody (C-term) in mouse cerebellum tissue lysates (35ug/lane). APPL1 (arrow) was detected using the purified Pab.
Application
APPL1 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the APPL1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
APPL1 Antibody (C-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
