Application
Western blot analysis of ATF2-pS44 in mouse liver tissue lysates (35ug/lane). ATF2 (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with ATF2 Antibody (S44) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | ATF2 Antibody (S44) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CREB2, CREBP1 |
|---|---|
| Alternative Names | ATF2 CREB2 CREBP1 Cyclic AMP-dependent transcription factor ATF-2 Activating transcription factor 2 Cyclic AMP-responsive element-binding protein 2 HB16 cAMP response element-binding protein CRE-BP1 |
| Molecular Weight(MW) | 54537 Da |
| Function | Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'- GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex |
| Tissue Specificity | Abundant expression seen in the brain. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 1386 |
|---|
Application
Western blot analysis of ATF2-pS44 in mouse liver tissue lysates (35ug/lane). ATF2 (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with ATF2 Antibody (S44) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
