BAK1 BAK BCL2L7 CDN1 Bcl-2 homologous antagonist/killer Apoptosis regulator BAK Bcl-2-like protein 7
Molecular Weight(MW)
23409 Da
Function
In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis
Tissue Specificity
Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle
Cellular Localization
Mitochondrion membrane; Single-pass membrane protein (Potential)