BECN1 Antibody (pT72) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the BECN1 antibody detected the BECN1 protein (arrow).
BECN1; GT197; Beclin-1; Coiled-coil myosin-like BCL2-interacting protein; Protein GT197
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
GT197
Alternative Names
BECN1 GT197 Beclin-1 Coiled-coil myosin-like BCL2-interacting protein Protein GT197
Molecular Weight(MW)
51896 Da
Function
Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus
Tissue Specificity
Ubiquitous.
Cellular Localization
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity)
BECN1 Antibody (pT72) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the BECN1 antibody detected the BECN1 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.