Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2
Tissue Specificity
This C11orf30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53~83 amino acids from the N-terminal region of human C11orf30.
Cellular Localization
Nucleus. Note=Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process
Western blot analysis of C11orf30 Antibody (N-term) in Ramos cell line lysates (35ug/lane). C11orf30 (arrow) was detected using the purified Pab.
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.